In the heart of the Domaine de Baulieu, where the Provençal soil still bears the memory of an ancient volcano, a cutting-edge regenerative science has emerged, born from botanical expertise. Advanced Botany Laboratories (LBA) explore the actions of plant stem cells, to reveal to the skin its own life intelligence.
Under the light ofAix en ProvenceThe Domaine de Baulieu spans 300 hectares of unspoiled nature, encompassing a 16th-century manor house built on basalt rock originating from Provence's only volcano. The exceptional biodiversity of the Domaine de Baulieu is captivating, and its soil, rich in silica, magnesium, and calcium, is home to a water with regenerative properties: Eau de Baulieu.
It is in this unique environment that the philosophy of Advanced Botany Laboratories : uniting biotechnology, science, and nature to create cosmetics dedicated to skin longevity. Heirs to the work of Joseph Pitton de Tournefort, who resided at the Baulieu estate, the scientists working for LBA pursue the same dream: to study and understand the incredible regenerative capacity of plant species cultivated on the estate in order to incorporate them into cutting-edge cosmetic formulas to serve the regenerative capacity of the skin.
Joseph Pitton de Tournefort (1656-1708) was, during his lifetime, one of the founding masters of modern botany. He was to the plant world what an architect is to buildings: a master who rigorously organizes and structures. Born in Aix-en-Provence and passionate from a young age about the plants of the Mediterranean hills, he established himself in Paris as a professor at the Jardin du Roi Soleil (Garden of the Sun King). There, he revolutionized the study of plants by proposing a classification based on their structure. Tournefort left behind a major body of work and a name associated with numerous plants, a symbol of a naturalist who ushered botany into the scientific age.
Biotechnology at the service of life
At the LBA Research and Innovation Center, two experimental gardens—the Herb Garden and the Botanical Exploration Garden—serve as open-air laboratories. Scientists observe the fascinating ability of plants to repair themselves and regenerate after adversity, and extract the plant stem cells that form the core of the brand's regenerative skincare formulas. These cells, derived from lily, peony, iris, and tuberose, are cultivated in vitro to preserve their purity and potency.
From this culture emerges an exclusive biobank, where each stem cell is traced, analyzed, and stabilized; a veritable living collection dedicated to beauty. A single plant cell contains within it the complete code for rebirth, and by cultivating it, we unleash the infinite potential of life, without ever depleting the natural resource. " explains Sophie Agat, Director of Research and Innovation.
The extracts obtained are concentrated in active molecules capable of acting on skin regeneration mechanisms, restarting energy metabolism and
to improve intercellular communication.
NEO-REGEN: an exclusive technology that activates the skin's natural regenerative abilities
The result of a collaboration with the Dr. Jean-Marc Lemaître (INSERM), world expert in cellular aging, co-director of the Institute of Regenerative Medicine in Montpellier and doctor at INSERM (National Institute of Health and Medical Research), NEO-REGEN technology is at the heart of every LBA treatment. This innovation combines the power of lily and peony stem cells with Baulieu Water, encapsulated in biomimetic liposomes (a kind of carrier of active ingredients in perfect affinity with the skin).
What about testing? Dr. Lemaître has developed a unique analysis and testing platform that uses the Skin Organoid, allowing for the evaluation of the efficacy of active ingredients and skincare products under conditions remarkably close to those of living organisms. Thanks to this technology, it has been proven that NEO-REGEN technology modulates 136 genes involved in skin aging. These discoveries place Laboratoires Botanique Avancée among the pioneers of exceptional regenerative cosmetics. A scientific approach, but also a profoundly philosophical one: considering beauty as a biological process, not merely appearance.
The proven effectiveness of cutting-edge cosmetics
In the laboratories of this field, formulation becomes an art. Each product contains up to 30% active ingredients, an exceptional level in high-end cosmetics. The textures are biomimetic, designed to blend with the skin and gradually release the active ingredients. Instrumental tests conducted over several months reveal significant results:
+53% firmness
–27% reduction in wrinkles
+47% measured brightness
+34% lasting hydration
« We advocate proof rather than promises ", emphasizes the LBA Expert Committee through its spokesperson Christiane Montastier Doctor of Pharmacy
Regenerative rituals: the art of care according to LBA
At Laboratoires Botanique Avancée, beauty is viewed as an inner movement. Each treatment protocol is based on a core belief: the skin is reactivated by the body's movement. Therapists work on fascial mobility, fluid circulation, and consequently, posture, releasing tension and stagnation to restore cellular energy. This anatomical work, combined with biotechnological active ingredients, creates a profound resonance: the skin regenerates from within.
Facial care
The Sap The Neo-Regen treatment acts like a regenerative skin sap (60, 90 or 120 min)
The brand's signature treatment, a true testament to LBA's expertise. Its techniques work with the silk cocoon, anti-adhesion kneading, regenerative massage, and fasciatherapy to awaken the skin's respiration, redefine facial contours, and restore radiance to the complexion. A comprehensive ritual that restructures, plumps, and revitalizes the skin.
The Outbreak : Fatigue-fighting treatment (60, 90 or 120 min)
A targeted muscle treatment to release tension and restore volume. Five strategic areas of the face and upper body are precisely worked for a more upright posture and rested features. Ideal after a long journey or a period of intense stress.
The Dew Radiance treatment (30 min)
A short, refreshingly radiant treatment. Inspired by the rolling massage technique, it activates microcirculation, refines skin texture, and instantly restores radiance and vitality to the face. A true "skin awakening."
Face & body care
The Aura: Holistic regenerative treatment (90 or 120 min)
Combining facial and body massage, this comprehensive ritual harmonizes the body's energies through fasciatherapy, lymphatic drainage, and acupressure. Skin and muscles breathe again, the body realigns, and the mind finds peace. A regenerative interlude of rare intensity.
The Chrysalis: Holistic Exfoliation (60 min)
A purifying and regenerating ritual for the face and body. This exfoliating treatment awakens cell renewal and envelops the skin in a silky veil. The result: a renewed skin feel and an immediate radiance.
Massages
Awakening Circulatory & postural massage (60, 90 or 120 min)
Gentle work on the fascia to restore lightness and realign the body deep within. Tensions dissolve, breath expands, and posture regains its balance.
Roots Deep tissue muscle relaxation massage (60 or 90 min)
Intensive deep tissue massage focused on releasing chronic tension. A powerful approach, ideal for athletes and those who enjoy firm pressure. The body feels grounded, vitality is awakened.
French excellence and sustainability as a legacy
LBA embodies a rare vision of luxury: that of sustainable refinement. The refillable containers, designed like works of art, are made in France in workshops certified as Living Heritage Companies. Each lid requires fifteen days of handcrafting, using infinitely recyclable aluminum. The formulas, 95% vegan and natural, are free of silicones, PEGs, and endocrine disruptors. Their design follows a demanding eco-design principle, where performance and respect for life are one.
Regenerative beauty, a new definition of premium skincare
From December 2025, the first ones LBA Spas will be created in the Airelles Houses: first in Courchevel, then in Versailles.
Each treatment will be designed as an exceptional experience: Airelles hospitality, signature LBA protocols, highly active formulas, sensory textures…
By combining science and nature, Laboratoires Botanique Avancée has invented a new kind of cosmetics inspired by living organisms, rooted in biotechnology where every gesture becomes a ritual. The skin regains its original radiance, and beauty, its profound meaning: that of a renewed connection with life itself.
Combining biotechnological precision, proven efficacy, and sensory experience, the brand embodies the vision of a new luxury, where the challenge of eco-responsibility, science, naturalness, and sensory refinement has been met.
www.laboratoires-botanique-avancee.com
Ema Lynnx
Photos: Patrick Koune
